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British Journal of Anaesthesia, Vol 84, Issue 3 405-406, Copyright © 2000 by Oxford University Press

ARTICLES

Rectally administered dimenhydrinate reduces postoperative vomiting in children after strabismus surgery

A Schlager, G Mitterschiffthaler and F Puhringer
Department of Anaesthesia and Intensive Care Medicine, Leopold Franzens University of Innsbruck, Austria.

We have investigated the effectiveness of rectally administered dimenhydrinate on postoperative vomiting in children undergoing strabismus surgery, in a double-blind, randomized, placebo-controlled study. In one group, dimenhydrinate 50 mg was administered rectally 30 min before starting anaesthesia, whereas in the control group, placebo suppositories were given. Children who received dimenhydrinate showed a significantly (P < 0.001) lower incidence of vomiting (15%) than those in the control group (75%). We conclude that rectal administration of dimenhydrinate is an effective means of reducing postoperative vomiting in children undergoing strabismus surgery.
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