Skip Navigation

This Article
Right arrow Full Text (PDF)
Right arrow E-Letters: Submit a response to the article
Right arrow Alert me when this article is cited
Right arrow Alert me when E-letters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in ISI Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrow Search for citing articles in:
ISI Web of Science (5)
Right arrowRequest Permissions
Right arrow Disclaimer
Google Scholar
Right arrow Articles by Wu, R. S.
Right arrow Articles by Tan, P. P.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Wu, R. S.
Right arrow Articles by Tan, P. P.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

British Journal of Anaesthesia, Vol 84, Issue 3 358-362, Copyright © 2000 by Oxford University Press

ARTICLES

Effects of fenoterol and ipratropium on respiratory resistance of asthmatics after tracheal intubation

RS Wu, KC Wu, TK Wong, YH Tsai, RK Cheng, MJ Bishop and PP Tan
China Medical College Hospital, Taichung, Taiwan, Republic of China.

We have studied the effects of a beta-agonist, fenoterol, and a cholinergic antagonist, ipratropium, on post-intubation total respiratory system resistance (Rrs) in asthmatics who developed increased Rrs after tracheal intubation. Sixteen stable asthmatics in whom Rrs increased after intubation were allocated randomly to receive either 10 puffs of fenoterol (group F) or 10 puffs of ipratropium (group IB) via a metered dose inhaler 5 min after intubation. Anaesthesia was induced and maintained with propofol i.v. Rrs was recorded before treatment and again 5, 15 and 30 min after treatment. Rrs decreased significantly from pretreatment values by mean 53 (SD 8)%, 53 (7)% and 58 (6)% at 5, 15 and 30 min, respectively, in group F, but declined by only 12 (6)%, 15 (4)% and 17 (5)% in group IB. At all times after treatment, patients in the fenoterol group had significantly lower Rrs values than those in the ipratropium group. We conclude that increased Rrs after tracheal intubation in asthmatics can be reduced effectively by treatment with fenoterol. A secondary finding of our study was that even after induction of anaesthesia with propofol, patients with a history of asthma may develop high Rrs.
Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 Proc Am Thorac SocHome page
B. Brenner, T. Corbridge, and A. Kazzi
Intubation and Mechanical Ventilation of the Asthmatic Patient in Respiratory Failure
Proceedings of the ATS, August 1, 2009; 6(4): 371 - 379.
[Full Text] [PDF]

Home page
 Anesth. Analg.Home page
P. Scalfaro, P. D. Sly, C. Sims, and W. Habre
Salbutamol Prevents the Increase of Respiratory Resistance Caused by Tracheal Intubation During Sevoflurane Anesthesia in Asthmatic Children
Anesth. Analg., October 1, 2001; 93(4): 898 - 902.
[Abstract] [Full Text] [PDF]

Home page
 Anesth. Analg.Home page
M. J. Bishop, G. A. Rooke, W. Habre, and P. D. Sly
Sevoflurane for Patients with Asthma Response
Anesth. Analg., April 1, 2000; 91(1): 245 - 246.
[Full Text] [PDF]


Disclaimer: Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.