British Journal of Anaesthesia, Vol 84, Issue 2 239-241, Copyright © 2000 by Oxford University Press
KL MacKinnon, Z Molnar, D Lowe, ID Watson and E Shearer
We have investigated the use of microalbuminuria as a predictor of outcome
in a pilot study involving 50 critically ill patients in a six- bed
hospital intensive care unit (ICU). Urinary microalbumin:creatinine (M:Cr)
ratios measured only 6 h after admission to the ICU demonstrated a
significant difference (P = 0.01) between survivors and non- survivors,
allowing rapid identification of patients at increased risk of developing
organ failure and at greater risk of death. This work suggests that earlier
identification of these patients using a rapid, simple, inexpensive
biochemical test is possible; if confirmed in a larger study, it may be
that clinical interventions can be targeted at those most likely to
benefit.
ARTICLES
Use of microalbuminuria as a predictor of outcome in critically ill patients
Department of Clinical Biochemistry, University Hospital Aintree, Liverpool, UK.
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