British Journal of Anaesthesia, Vol 82, Issue 5 672-678, Copyright © 1999 by The Board of Management and Trustees of the British Journal of Anaesthesia
R. J. Gajraj, M. Doi, H. Mantzaridis and GNC. Kenny
We have compared the auditory evoked potential index (AEPIndex) and
bispectral index (BIS) for monitoring depth of anaesthesia in spontaneously
breathing surgical patients. Twenty patients (aged 17-49 yr) undergoing day
surgery were anaesthetized with computer-controlled infusions of propofol.
The mean (SD and range) of each measurement was determined during
consciousness and unconsciousness and at specific times during the
perioperative period. Mean values for AEPIndex during consciousness and
unconsciousness were 74.5 (SD 14.7) 36.7 (7.1), respectively. BIS had mean
values of 89.5 (SD 4.6) during consciousness and 48.8 (16.4) during
unconsciousness. AEPIndex and BIS were greater during consciousness
compared with during unconsciousness. The average awake values of AEPIndex
were significantly higher than all average values during unconsciousness
but this was not the case for BIS. BIS increased gradually during emergence
from anaesthesia and may therefore be able to predict recovery of
consciousness at the end of anaesthesia. AEPIndex was more able to detect
the transition from unconsciousness to consciousness.
CLINICAL INVESTIGATIONS
Comparison of bispectral EEG analysis and auditory evoked potentials for monitoring depth of anaesthesia during propofol anaesthesia
Department of Anaesthesia, General Infirmary at Leeds, Great George Street, Leeds LSI 3EX, UK; Department of Anaesthesiology and Intensive Care, Hamamatsu University School of Medicine, 3600 Handa, Hamamatsu 431-31, Japan; Department of Anaesthetics, Law Hospital, Carluke, Lanarkshire ML8 5ER, UK; Glasgow University Department of Anaesthesia, Royal Infirmary, 8-16 Alexandra Parade, Glasgow G31 2ER, UK
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