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British Journal of Anaesthesia, Vol 82, Issue 4 586-590, Copyright © 1999 by The Board of Management and Trustees of the British Journal of Anaesthesia

CLINICAL INVESTIGATIONS

Combined field block and i.p. instillation of ropivacaine for pain management after laparoscopic sterilization

T. Callesen, D. Hjort, T. Mogensen, L. Schouenborg, D. Nielsen, H. Reventlid and H. Kehlet
Department of Anaesthesiology, Department of Surgical Gastroenterology and Department of Gynaecology and Obstetrics, H:S Hvidovre University Hospital, DK-2650 Hvidovre, Denmark; Astra Pain Control, S-151 85 Sodertalje, Sweden

We have studied the effect of ropivacaine for combined port site and mesosalpinx infiltration, and peritoneal instillation on pain, nausea and vomiting after laparoscopic sterilization, in a double-blind, placebo-controlled study in 80 patients. The total dose of ropivacaine was 285 mg. All patients received intra- and postoperative NSAID in fixed doses. Abdominal and shoulder pain, nausea and vomiting were recorded during the first 8 h after operation and in a diary for 3 days. In the ropivacaine group, abdominal pain scores were lower during the first 4 h (P < 0.00001), additional use of morphine was less (P < 0.001) and fewer patients had nausea or vomiting during the first 72 h (five vs 14; P < 0.05). There were no signs of local anaesthetic toxicity.
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