British Journal of Anaesthesia, Vol 82, Issue 4 575-579, Copyright © 1999 by The Board of Management and Trustees of the British Journal of Anaesthesia
A. Hiller, K. Karjalainen, M. Balk and P. H. Rosenberg
Transient neurotoxicity of concentrated local anaesthetics has been thought
to be the main reason for transient neurological symptoms after spinal
anaesthesia. Profound musculoligamental relaxation by high doses of local
anaesthetics may contribute to the development of postoperative
musculoskeletal pain. In order to evaluate the role of the loss of strength
of the supportive structures of the spine in the development of transient
neurological symptoms, 60 patients (ASA I-II) undergoing minor orthopaedic,
varicose vein or inguinal hernia operations were allocated randomly to
receive spinal anaesthesia with hyperbaric lidocaine 50 mg ml-1 (85-100 mg)
or balanced general anaesthesia with neuromuscular block. Patients were
interviewed 24 h later and after 1 week they returned a written
questionnaire. Transient neurological symptoms, consisting of pain in the
buttocks or pain radiating symmetrically to the lower extremities, occurred
in eight patients (27%) receiving spinal anaesthesia and in one patient
(3%) receiving general anaesthesia (P < 0.05). We conclude that a
transient neurotoxic effect of hyperbaric lidocaine 50 mg ml-1 is probably
the main reason for transient neurological symptoms after spinal
anaesthesia but musculoligamental relaxation may contribute to the
development of low back or leg pain after both anaesthetic techniques.
CLINICAL INVESTIGATIONS
Transient neurological symptoms after spinal anaesthesia with hyperbaric 5% lidocaine or general anaesthesia
Department of Anaesthesia, Helsinki University Central Hospital, Otolaryngological Hospital, Haartmaninkatu 4E, FIN-00290 Helsinki, Finland; Department of Anaesthesia, Kuusankoski District Hospital, FIN-45750 Sairaalamaki, Finland; Department of Anaesthesia, Paijat-Hame Central Hospital, Keskussairaalankatu 7, FIN-15850 Lahti, Finland; Department of Anaesthesiology, Helsinki University Central Hospital, FIN-00290 Helsinki, Finland
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