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British Journal of Anaesthesia, Vol 82, Issue 3 442-443, Copyright © 1999 by The Board of Management and Trustees of the British Journal of Anaesthesia

SHORT COMMUNICATIONS

Haemodynamic changes after tracheal intubation in cigarette smokers compared with non-smokers

C. H. Laxton, Q. Milner and P. J. Murphy
Royal Devon and Exeter Hospital, Wonford, Exeter, UK

We have studied the haemodynamic changes in response to tracheal intubation in 60 ASA I women undergoing elective gynaecological surgery; 30 women smoked more than 10 cigarettes a day, while the other 30 were non-smokers. Immediately after intubation, heart rate of smokers (mean 102.0 (SD 17) beat min-1) was significantly greater (P < 0.01) than that of non-smokers (mean 91.0 (12.3) beat min-1). This may be clinically important in smokers who are at risk of ischaemic heart disease and also relevant for future studies investigating haemodynamic responses to intubation.
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