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British Journal of Anaesthesia, Vol 82, Issue 3 432-434, Copyright © 1999 by The Board of Management and Trustees of the British Journal of Anaesthesia

SHORT COMMUNICATIONS

Iontophoretically applied lidocaine reduces pain on propofol injection

P. J. Sadler, H. M. Thompson, P. Maslowski, A. Liddle and D. J. Rowbotham
University Department of Anaesthesia, Infirmary Road, Leicester Royal Infirmary, Leicester LE1 5WW, UK

We have compared iontophoretically and locally applied lidocaine for relief of pain on propofol injection. Pain was assessed on insertion of a 20-gauge i.v. cannula and at 10-s intervals for 30 s after injection of propofol. Pain scores on cannulation were significantly less in the iontophoresis group (median 1.1) than in the sham (control) group (median 2.8) (P < 0.005). Pain after injection of propofol was significantly reduced at 10 (P < 0.002), 20 (P < 0.001) and 30 s (P < 0.001). We conclude that iontophoretically applied lidocaine decreased the pain of cannulation and propofol injection.
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