Skip Navigation

This Article
Right arrow Full Text (PDF)
Right arrow E-Letters: Submit a response to the article
Right arrow Alert me when this article is cited
Right arrow Alert me when E-letters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in ISI Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrow Search for citing articles in:
ISI Web of Science (21)
Right arrowRequest Permissions
Right arrow Disclaimer
Google Scholar
Right arrow Articles by Sneyd, J. R.
Right arrow Articles by Andrews, CJH.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Sneyd, J. R.
Right arrow Articles by Andrews, CJH.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

British Journal of Anaesthesia, Vol 81, Issue 3 361-364, Copyright © 1998 by The Board of Management and Trustees of the British Journal of Anaesthesia

CLINICAL INVESTIGATIONS

An open, randomized comparison of alfentanil, remifentanil and alfentanil followed by remifentanil in anaesthesia for craniotomy

J. R. Sneyd, A. Whaley, H. L. Dimpel and CJH. Andrews
Plymouth Postgraduate Medical School, Plymouth; Department of Anaesthesia, Derriford Hospital, Plymouth PL6 8DH

We studied 52 adults undergoing elective craniotomy, allocated randomly to one of three opioid treatments: alfentanil 50 micrograms kg-1 followed by 0.833 microgram kg-1 min-1 until dural closure (group Alf.); alfentanil 50 micrograms kg-1 followed by 0.833 microgram kg-1 min-1 for 2 h, then remifentanil 0.25 microgram kg-1 min-1 (group Alf.- Remi.); or remifentanil 1 microgram kg-1 followed by 0.5 microgram kg-1 min-1 reducing to 0.25 microgram kg-1 min-1 after craniotomy (group Remi.). Anaesthesia was maintained with infusion of propofol and 66% nitrous oxide in oxygen. Infusions of propofol and remifentanil were stopped at head bandaging. Group Remi. had the least intraoperative haemodynamic responses and group Alf. the most (P < 0.05). Times to tracheal extubation and obey commands were similar in all groups. In all patients in group Alf.-Remi. and group Remi., the trachea was extubated 27 min from the end of anaesthesia; three patients in group Alf. were slower to recover. Use of analgesia in the recovery room and time to transfer to the neurosurgical unit were similar in the three groups.
Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 Br J AnaesthHome page
J. R. Sneyd, C. J. H. Andrews, and T. Tsubokawa
Comparison of propofol/remifentanil and sevoflurane/remifentanil for maintenance of anaesthesia for elective intracranial surgery
Br. J. Anaesth., June 1, 2005; 94(6): 778 - 783.
[Abstract] [Full Text] [PDF]

Home page
 Anesth. Analg.Home page
P. Talke, J. E. Caldwell, R. Brown, B. Dodson, J. Howley, and C. A. Richardson
A Comparison of Three Anesthetic Techniques in Patients Undergoing Craniotomy for Supratentorial Intracranial Surgery
Anesth. Analg., August 1, 2002; 95(2): 430 - 435.
[Abstract] [Full Text] [PDF]

Home page
 Anesth. Analg.Home page
A. Y. Bekker, P. Berklayd, I. Osborn, M. Bloom, J. Yarmush, and H. Turndorf
The Recovery of Cognitive Function After Remifentanil- Nitrous Oxide Anesthesia Is Faster than After an Isoflurane-Nitrous Oxide-Fentanyl Combination in Elderly Patients
Anesth. Analg., July 1, 2000; 91(1): 117 - 122.
[Abstract] [Full Text] [PDF]

Home page
 Anesth. Analg.Home page
G. Balakrishnan, P. Raudzens, S. K. Samra, K. Song, J. A. Boening, V. Bosek, B. D. Jamerson, and D. S. Warner
A Comparison of Remifentanil and Fentanyl in Patients Undergoing Surgery for Intracranial Mass Lesions
Anesth. Analg., July 1, 2000; 91(1): 163 - 169.
[Abstract] [Full Text] [PDF]


Disclaimer: Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.