British Journal of Anaesthesia, Vol 79, Issue 3 306-310, Copyright © 1997 by The Board of Management and Trustees of the British Journal of Anaesthesia
M. Tugrul, E. Camci, H. Karadeniz, M. Senturk, K. Pembeci and K. Akpir
Pressure controlled ventilation (PCV) is an alternative mode of ventilation
which is used widely in severe respiratory failure. In this study, PCV was
used for one-lung anaesthesia and its effects on airway pressures, arterial
oxygenation and haemodynamic state were compared with volume controlled
ventilation (VCV). We studied 48 patients undergoing thoracotomy. After
two-lung ventilation with VCV, patients were allocated randomly to one of
two groups. In the first group (n = 24), one-lung ventilation was started
by VCV and the ventilation mode was then switched to PCV. Ventilation modes
were performed in the opposite order in the second group (n = 24). We
observed that peak airway pressure (P = 0.000001), plateau pressure (P =
0.01) and pulmonary shunt (P = 0.03) were significantly higher during VCV,
whereas arterial oxygen tension (P = 0.02) was significantly higher during
PCV. Peak airway pressure (Paw) decreased consistently during PCV in every
patient and the percentage reduction in Paw was 4-35% (mean 16.1 (SD 8.4)
%). Arterial oxygen tension increased in 31 patients using PCV and the
improvement in arterial oxygenation during PCV correlated inversely with
preoperative respiratory function tests. We conclude that PCV appeared to
be an alternative to VCV in patients requiring one-lung anaesthesia and may
be superior to VCV in patients with respiratory disease.
CLINICAL INVESTIGATIONS
Comparison of volume controlled with pressure controlled ventilation during one-lung anaesthesia
Department of Anaesthesiology and Intensive Care, University of Medical Faculty, Turkiye
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