Skip Navigation

This Article
Right arrow Full Text (PDF)
Right arrow E-Letters: Submit a response to the article
Right arrow Alert me when this article is cited
Right arrow Alert me when E-letters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in ISI Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrow Search for citing articles in:
ISI Web of Science (4)
Right arrowRequest Permissions
Right arrow Disclaimer
Google Scholar
Right arrow Articles by McBeth, C.
Right arrow Articles by Watkins, TGL.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by McBeth, C.
Right arrow Articles by Watkins, TGL.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

British Journal of Anaesthesia, Vol 77, Issue 5 672-674, Copyright © 1996 by The Board of Management and Trustees of the British Journal of Anaesthesia

CASE REPORTS

Isoflurane for sedation in a case of congenital myasthenia gravis

C. McBeth and TGL. Watkins
Department of Anaesthesia, East Glamorgan Hospital, Church Village, Pontypridd, Mid Glamorgan CF38 1AB

We describe the use of isoflurane for the management of a 3-yr-old boy with congenital myasthenia gravis who required ventilation for pneumonia. While in the intensive care unit he was sedated with isoflurane for 5 days (81 MAC-h). This provided a safe, easily controllable method of sedation which avoided the use of neuromuscular blocking agents and appeared to have no significant side effects during use. However, after it was stopped the patient developed a fine, self- limiting tremor which lasted for 2 days. Previous reports of paediatric patients sedated with isoflurane suggest that prolonged exposure may result in temporary dose-dependent neurological dysfunction, including hallucinations, ataxia and non-purposeful movements.
Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 Anesth. Analg.Home page
A. W. Loepke and S. G. Soriano
An Assessment of the Effects of General Anesthetics on Developing Brain Structure and Neurocognitive Function
Anesth. Analg., June 1, 2008; 106(6): 1681 - 1707.
[Abstract] [Full Text] [PDF]

Home page
 Br J AnaesthHome page
N. P. Hirsch
Neuromuscular junction in health and disease
Br. J. Anaesth., July 1, 2007; 99(1): 132 - 138.
[Abstract] [Full Text] [PDF]

Home page
 Br J AnaesthHome page
A. Meiser, C. Sirtl, M. Bellgardt, S. Lohmann, A. Garthoff, J. Kaiser, P. Hugler, and H. J. Laubenthal
Desflurane compared with propofol for postoperative sedation in the intensive care unit
Br. J. Anaesth., March 1, 2003; 90(3): 273 - 280.
[Abstract] [Full Text] [PDF]


Disclaimer: Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.