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British Journal of Anaesthesia, Vol 77, Issue 5 669-671, Copyright © 1996 by The Board of Management and Trustees of the British Journal of Anaesthesia

CASE REPORTS

Use of rocuronium in a pregnant patient with an open eye injury, receiving magnesium medication, for preterm labour

R. R. Gaiser and E. H. Seem
Department of Anaesthesia, Hospital of the University of Pennsylvania, 3400 Spruce Street, Philadelphia, PA 19104, USA

We present a case where rocuronium 80 mg (3 x ED95) was used in a rapid sequence induction in a 80-kg pregnant patient with an open eye injury. The patient was also receiving magnesium 2 g h-1 i.v. for preterm labour. The expected duration for neuromuscular block of rocuronium in the absence of magnesium would be approximately 53 min; with infusion of magnesium, the duration of neuromuscular block was prolonged four- fold (215 min). It is important to remember that magnesium potentiates the effects of all non-depolarizing neuromuscular blocking agents, including rocuronium.
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