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British Journal of Anaesthesia, Vol 77, Issue 5 586-590, Copyright © 1996 by The Board of Management and Trustees of the British Journal of Anaesthesia


CLINICAL INVESTIGATIONS

Comparison of caudal bupivacaine and diamorphine with caudal bupivacaine alone for repair of hypospadias

A. A. Kelleher, A. Black, S. Penman and R. Howard
St Georges Hospital, London SW17 OQT; The Hospital for Sick Children Trust, Great Ormond Street, London WCIN 3JH

Forty-five boys undergoing repair of hypospadias were allocated randomly to one of two groups. After induction of anaesthesia, 22 patients received 0.25% caudal bupivacaine 0.5 ml kg-1 and diamorphine 30 micrograms kg-1 and the remaining 23 patients received 0.25% caudal bupivacaine 0.5 ml kg-1 alone. Pain scores (Children's Hospital of Eastern Ontario Pain Scale), sedation scores, ventilatory frequency, analgesic requirements and associated side effects were recorded for the first 24 h after operation. The two groups were indistinguishable in age, weight and duration of surgery. There was a statistically significant reduction in early pain scores. There was also a statistically significant increase in the time to first passage of urine in those boys in the diamorphine group who were not catheterized during operation.
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D. A. H. de Beer and M. L. Thomas
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Br. J. Anaesth., April 1, 2003; 90(4): 487 - 498.
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