British Journal of Anaesthesia, Vol 76, Issue 6 872-873, Copyright © 1996 by The Board of Management and Trustees of the British Journal of Anaesthesia
M. Gentili and F. Bonnet
We have conducted a double-blind, randomized study in two groups of 20
patients each, undergoing hip surgery during spinal anaesthesia, to compare
the incidence of urinary retention after spinal morphine or clonidine.
Patients received 0.5% spinal bupivacaine 15 mg combined with either
clonidine 75 micrograms or morphine 0.2 mg. After operation, patients were
examined for micturition, bladder distension, or both; when they failed to
void, they received naloxone 0.2 mg, and if bladder distension persisted, a
catheter was inserted. At 12 h, all patients in the morphine group but only
five in the clonidine group had bladder distension, and at 24 h this was
present in seven and one patient in the morphine and clonidine groups,
respectively (P < 0.001). Naloxone was given in 16 and one, and a
catheter was placed in one and six patients in the morphine and clonidine
groups, respectively (P < 0.001). We conclude that spinal clonidine
impaired bladder function to a lesser extent than morphine.
SHORT COMMUNICATIONS
Spinal clonidine produces less urinary retention than spinal morphine
Departement d'Anesthesie, Hopital Henri Mondor, Creteil, France
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