British Journal of Anaesthesia, Vol 75, Issue 5 552-555, Copyright © 1995 by The Board of Management and Trustees of the British Journal of Anaesthesia
B. Lyons, D. Lohan, C. G. Flynn, G. P. Joshi, T. M. O'Brien and M. McCarroll
Intra-articular morphine has been shown to provide prolonged analgesia
after arthroscopic knee surgery; the addition of local anaesthetic agents
has been reported to improve this analgesic effect. Pethidine possesses
local anaesthetic properties, and therefore this study was designed to
evaluate its analgesic efficacy after arthroscopic meniscectomy. Sixty
patients were allocated randomly to receive intra- articular injections of
pethidine 50 mg, morphine 5 mg or saline after elective arthroscopic
meniscectomy. Postoperative pain was assessed using an interval visual
analogue scale and measuring analgesic requirements. Both treatment groups
had significantly lower pain scores compared with the control group.
Patients in the pethidine group had lower pain scores than those in the
morphine group at 0.5, 1 and 2 h, but significantly higher scores at 12 and
24 h. These observations suggest that the local anaesthetic effect of
pethidine may be responsible for the improved early analgesia, but its
duration of action appears to be less than that of morphine.
CLINICAL INVESTIGATIONS
Intra-articular analgesia for arthroscopic meniscectomy
Department of Anaesthesia, Cappagh Orthopaedic Hospital, Cappagh, Dublin 11, Ireland; Department of Surgery, Cappagh Orthopaedic Hospital, Cappagh, Dublin 11, Ireland;
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