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British Journal of Anaesthesia, Vol 75, Issue 4 498-499, Copyright © 1995 by The Board of Management and Trustees of the British Journal of Anaesthesia

CASE REPORTS

Mivacurium chloride and myotonic dystrophy

N. A. Watt and RPF. Scott
Department of Anaesthetics, Salisbury District Hospital, Salisbury, Wiltshire SP2 8BJ

We describe the successful use of the short-acting, non-depolarizing neuromuscular blocking agent, mivacurium, in a patient with myotonic dystrophy. Increased sensitivity to mivacurium was demonstrated using train-of-four monitoring, with a single dose of mivacurium providing adequate block for 90 min of surgery. Spontaneous recovery appeared prolonged with a recovery index (25-75% T1) of 10 min and a recovery time (5-95% T1) of 30 min. The use of reversal agents and anticholinergic agents was avoided.
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