Skip Navigation

This Article
Right arrow Full Text (PDF)
Right arrow E-Letters: Submit a response to the article
Right arrow Alert me when this article is cited
Right arrow Alert me when E-letters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in ISI Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrow Search for citing articles in:
ISI Web of Science (106)
Right arrowRequest Permissions
Right arrow Disclaimer
Google Scholar
Right arrow Articles by Jackson, R.
Right arrow Articles by Thorburn, J.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Jackson, R.
Right arrow Articles by Thorburn, J.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

British Journal of Anaesthesia, Vol 75, Issue 3 262-265, Copyright © 1995 by The Board of Management and Trustees of the British Journal of Anaesthesia

CLINICAL INVESTIGATIONS

Volume preloading is not essential to prevent spinal-induced hypotension at Caesarean section

R. Jackson, J. A. Reid and J. Thorburn
Department of Anaesthesia, Queen Mother's Hospital, Yorkhill, Glasgow G11 6NT

We have compared the protective effect of 1000 ml preload with 200 ml preload of crystalloid solution, administered during the 10 min before spinal anaesthesia was induced, in 60 healthy women with no fetal compromise undergoing elective Caesarean section. The spinal anaesthetic was managed identically in both groups by an anaesthetist who was unaware of the volume of fluid administered. A prophylactic infusion of ephedrine 60 mg in Hartmann's solution 500 ml was given according to maternal arterial pressure. Hypotension was defined as > or = 30% reduction from baseline or < 90 mm Hg, and was treated by i.v. ephedrine bolus doses. There was no significant difference in ephedrine requirements between the two groups or in the incidence, severity or duration of hypotension: 10 women in the 1000-ml group, five episodes lasting > or = 3 min compared with nine women in the 200-ml group, four lasting > or = 3 min. There was no difference between neonates in each group. We have now abandoned the routine of preloading before regional anaesthesia.
Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 Anesth. Analg.Home page
P. Tamilselvan, R. Fernando, J. Bray, M. Sodhi, and M. Columb
The Effects of Crystalloid and Colloid Preload on Cardiac Output in the Parturient Undergoing Planned Cesarean Delivery Under Spinal Anesthesia: A Randomized Trial
Anesth. Analg., December 1, 2009; 109(6): 1916 - 1921.
[Abstract] [Full Text] [PDF]

Home page
 Anesth. Analg.Home page
S. M. Siddik-Sayyid, V. G. Nasr, S. K. Taha, R. A. Zbeide, J.-M. A. Shehade, A. A. Al Alami, F. H. Mokadem, F. W. Abdallah, A. S. Baraka, and M. T. Aouad
A Randomized Trial Comparing Colloid Preload to Coload During Spinal Anesthesia for Elective Cesarean Delivery
Anesth. Analg., October 1, 2009; 109(4): 1219 - 1224.
[Abstract] [Full Text] [PDF]

Home page
 Anesth. Analg.Home page
W. H. L. Teoh and A. T. H. Sia
Colloid Preload Versus Coload for Spinal Anesthesia for Cesarean Delivery: The Effects on Maternal Cardiac Output
Anesth. Analg., May 1, 2009; 108(5): 1592 - 1598.
[Abstract] [Full Text] [PDF]

Home page
 Br J AnaesthHome page
G. Sharwood-Smith and G. B. Drummond
Hypotension in obstetric spinal anaesthesia: a lesson from pre-eclampsia
Br. J. Anaesth., March 1, 2009; 102(3): 291 - 294.
[Full Text] [PDF]

Home page
 Anesth. Analg.Home page
B. S. Shin, J. S. Ko, M. S. Gwak, M. Yang, C. S. Kim, T. S. Hahm, S. M. Lee, H. S. Cho, S. T. Kim, J. H. Kim, et al.
The Effects of Prehydration on the Properties of Cerebrospinal Fluid and the Spread of Isobaric Spinal Anesthetic Drug
Anesth. Analg., March 1, 2008; 106(3): 1002 - 1007.
[Abstract] [Full Text] [PDF]

Home page
 Anesth. Analg.Home page
M. Van de Velde, D. Van Schoubroeck, J. Jani, A. Teunkens, C. Missant, and J. Deprest
Combined spinal-epidural anesthesia for cesarean delivery: dose-dependent effects of hyperbaric bupivacaine on maternal hemodynamics.
Anesth. Analg., July 1, 2006; 103(1): 187 - 190.
[Abstract] [Full Text] [PDF]

Home page
 Br J AnaesthHome page
T. Erkinaro, K. Makikallio, T. Kavasmaa, S. Alahuhta, and J. Rasanen
Effects of ephedrine and phenylephrine on uterine and placental circulations and fetal outcome following fetal hypoxaemia and epidural-induced hypotension in a sheep model
Br. J. Anaesth., December 1, 2004; 93(6): 825 - 832.
[Abstract] [Full Text] [PDF]

Home page
 Br J AnaesthHome page
W. D. Ngan Kee, K. S. Khaw, and F. F. Ng
Comparison of phenylephrine infusion regimens for maintaining maternal blood pressure during spinal anaesthesia for Caesarean section{dagger}
Br. J. Anaesth., April 1, 2004; 92(4): 469 - 474.
[Abstract] [Full Text] [PDF]

Home page
 Anesth. Analg.Home page
E. Lew, S.-W. Yeo, and E. Thomas
Combined Spinal-Epidural Anesthesia Using Epidural Volume Extension Leads to Faster Motor Recovery After Elective Cesarean Delivery: A Prospective, Randomized, Double-Blind Study
Anesth. Analg., March 1, 2004; 98(3): 810 - 814.
[Abstract] [Full Text] [PDF]

Home page
 Anesth. Analg.Home page
W. D. Ngan Kee, K. S. Khaw, F. F. Ng, and B. B. Lee
Prophylactic Phenylephrine Infusion for Preventing Hypotension During Spinal Anesthesia for Cesarean Delivery
Anesth. Analg., March 1, 2004; 98(3): 815 - 821.
[Abstract] [Full Text] [PDF]

Home page
 Anesth. Analg.Home page
J. Klasen, A. Junger, B. Hartmann, M. Benson, A. Jost, A. Banzhaf, M. Kwapisz, and G. Hempelmann
Differing Incidences of Relevant Hypotension with Combined Spinal-Epidural Anesthesia and Spinal Anesthesia
Anesth. Analg., May 1, 2003; 96(5): 1491 - 1495.
[Abstract] [Full Text] [PDF]

Home page
 Anesth. Analg.Home page
M. P. Vercauteren, H. C. Coppejans, and L. Sermeus
Anaphylactoid Reaction to Hydroxyethylstarch During Cesarean Delivery in a Patient with HELLP Syndrome
Anesth. Analg., March 1, 2003; 96(3): 859 - 861.
[Abstract] [Full Text] [PDF]

Home page
 Br J AnaesthHome page
K. Holte, N. E. Sharrock, and H. Kehlet
Pathophysiology and clinical implications of perioperative fluid excess
Br. J. Anaesth., October 1, 2002; 89(4): 622 - 632.
[Abstract] [Full Text] [PDF]

Home page
 Anesth. Analg.Home page
B. Hartmann, A. Junger, J. Klasen, M. Benson, A. Jost, A. Banzhaf, and G. Hempelmann
The Incidence and Risk Factors for Hypotension After Spinal Anesthesia Induction: An Analysis with Automated Data Collection
Anesth. Analg., June 1, 2002; 94(6): 1521 - 1529.
[Abstract] [Full Text] [PDF]

Home page
 Anesth. Analg.Home page
J. L. Mojica, H. J. Melendez, and L. E. Bautista
The Timing of Intravenous Crystalloid Administration and Incidence of Cardiovascular Side Effects During Spinal Anesthesia: The Results from a Randomized Controlled Trial
Anesth. Analg., February 1, 2002; 94(2): 432 - 437.
[Abstract] [Full Text] [PDF]

Home page
 Br J AnaesthHome page
W. D. N. Kee, K. S. Khaw, B. B. Lee, F. F. Ng, and M. M. S. Wong
Randomized controlled study of colloid preload before spinal anaesthesia for Caesarean section{dagger}
Br. J. Anaesth., November 1, 2001; 87(5): 772 - 774.
[Abstract] [Full Text] [PDF]

Home page
 Br J AnaesthHome page
C.-A. Ewaldsson and R. G. Hahn
Volume kinetics of Ringer's solution during induction of spinal and general anaesthesia
Br. J. Anaesth., September 1, 2001; 87(3): 406 - 414.
[Abstract] [Full Text] [PDF]

Home page
 Anesth. Analg.Home page
W. D. Ngan Kee, K. S. Khaw, B. B. Lee, M. M.S Wong, and F. F. Ng
Metaraminol Infusion for Maintenance of Arterial Blood Pressure During Spinal Anesthesia for Cesarean Delivery: The Effect of a Crystalloid Bolus
Anesth. Analg., September 1, 2001; 93(3): 703 - 708.
[Abstract] [Full Text] [PDF]

Home page
 Anesth. Analg.Home page
P. J. Morgan, S. H. Halpern, and J. Tarshis
The Effects of an Increase of Central Blood Volume Before Spinal Anesthesia for Cesarean Delivery: A Qualitative Systematic Review
Anesth. Analg., April 1, 2001; 92(4): 997 - 1005.
[Abstract] [Full Text] [PDF]

Home page
 Br J AnaesthHome page
B. T. Ayorinde, P. Buczkowski, J. Brown, J. Shah, and D. J. Buggy
Evaluation of pre-emptive intramuscular phenylephrine and ephedrine for reduction of spinal anaesthesia-induced hypotension during Caesarean section
Br. J. Anaesth., March 1, 2001; 86(3): 372 - 376.
[Abstract] [Full Text] [PDF]

Home page
 Anesth. Analg.Home page
W. D. N. Kee, K. S. Khaw, B. B. Lee, T. K. Lau, and T. Gin
A Dose-Response Study of Prophylactic Intravenous Ephedrine for the Prevention of Hypotension During Spinal Anesthesia for Cesarean Delivery
Anesth. Analg., June 1, 2000; 90(6): 1390 - 1395.
[Abstract] [Full Text] [PDF]

Home page
 Anesth. Analg.Home page
M. P. Vercauteren, H. C. Coppejans, V. H. Hoffmann, E. Mertens, and H. A. Adriaensen
Prevention of Hypotension by a Single 5-mg Dose of Ephedrine During Small-Dose Spinal Anesthesia in Prehydrated Cesarean Delivery Patients
Anesth. Analg., February 1, 2000; 90(2): 324 - 324.
[Abstract] [Full Text] [PDF]


Disclaimer: Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.