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British Journal of Anaesthesia, 1995, Vol. 74, No. 6 647-650
© 1995 The Board of Management and Trustees of the British Journal of Anaesthesia

other

Effect of transdermal hyoscine on nausea and vomiting after surgical correction of prominent ears under general anaesthesia

P. HONKAVAARA, MD, L. SAARNIVAARA, MD and U.-M. KLEMOLA, MD

Department of Anaesthesia, Otolaryngological Hospital, University of Helsinki Haartmaninkatu 4E, FIN-00290 Helsinki, Finland

Correspondence to P.H.

In a double-blind, randomized study, we have compared the efficacy of transdermal hyoscine with placebo in the reduction of nausea and vomiting in 50 patients, ASA I–II, after surgical correction of prominent ears under general anaesthesia. In the placebo group, 28%, 4% and 48% of patients suffered nausea, retching and vomiting, respectively, during the first 24 h after anaesthesia. The corresponding values in the hyoscine group were 12%, 0% and 16% (P > 0.01). In the placebo group more patients (48%) needed droperidol as an antiemetic compared with the hyoscine group (16%; P > 0.05). There was significantly more sedation in the hyoscine group.


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