Skip Navigation

This Article
Right arrow Full Text (PDF)
Right arrow E-Letters: Submit a response to the article
Right arrow Alert me when this article is cited
Right arrow Alert me when E-letters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrowRequest Permissions
Right arrow Disclaimer
Google Scholar
Right arrow Articles by HÖRMANN, Ch.
Right arrow Articles by BENZER, A.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by HÖRMANN, Ch.
Right arrow Articles by BENZER, A.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

British Journal of Anaesthesia, 1995, Vol. 74, No. 5 616-618
© 1995 The Board of Management and Trustees of the British Journal of Anaesthesia

other

Hyperventilation reverses the nitrous oxide-induced increase cerebral blood flow velocity in human volunteers

Ch. HÖRMANN, MD, Ch. SCHMIDAUER, MD, H. P. HARING, MD, S. SCHALOW, MD, M. SEIWALD, MD and A. BENZER, MD

Department of Anaesthesia, University of Innsbruck Anichstrasse 35, A-6020 Innsbruck, Austria
Department of Neurology, University of Innsbruck Anichstrasse 35, A-6020 Innsbruck, Austria
Department of Neurosurgery, University of Innsbruck Anichstrasse 35, A-6020 Innsbruck, Austria

Correspondence to A. B.

Because hypocapnia is routine during general anaesthesia for intracranial procedures, we have compared, in 1 3 healthy volunteers, the effect of normocapnia (PE'CO2 5.3 kPa) and hypocapnia (PE'CO2 3.3 kPa) on mean blood flow velocity in the middle cerebral artery (Vmca) during normoventilation and hyperventilation with air and with 50% nitrous oxide in oxygen. After replacement of air with 50% nitrous oxide in oxygen, there was an increase in mean Vmca during normoventilation (air: mean 68.23 (SD 16.98) cm s–1 vs nitrous oxide in oxygen: 90.69 (20.41) cm s–1; P < 0.01), whereas during hyperventilation mean Vmca values were similar regardless of the inhaled gas mixture (air: 43.46 (9.97) cm s–1 vs nitrous oxide in oxygen: 41.69 (8.08) cm s–1 Our data suggest that the nitrous oxide-induced increase in mean Vmca can be blocked by hyperventilation. (Br. J. Anaesth. 1995; 74: 616–618)


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 Anesth. Analg.Home page
C. Karsli, E. Wilson-Smith, I. Luginbuehl, and B. Bissonnette
The Effect of Nitrous Oxide on Cerebrovascular Reactivity to Carbon Dioxide in Children During Propofol Anesthesia
Anesth. Analg., September 1, 2003; 97(3): 694 - 698.
[Abstract] [Full Text] [PDF]

Home page
 Br J AnaesthHome page
I. H. Lorenz, C. Kolbitsch, M. Hinteregger, P. Bauer, M. Spiegel, T. J. Luger, C. Schmidauer, W. Streif, K. P. Pfeiffer, and A. Benzer
Remifentanil and nitrous oxide reduce changes in cerebral blood flow velocity in the middle cerebral artery caused by pain
Br. J. Anaesth., March 1, 2003; 90(3): 296 - 299.
[Abstract] [Full Text] [PDF]

Home page
 Anesth. Analg.Home page
H. R. Munoz, G. E. Nunez, J. E. de la Fuente, and M. G. Campos
The Effect of Nitrous Oxide on Jugular Bulb Oxygen Saturation During Remifentanil Plus Target-Controlled Infusion Propofol or Sevoflurane in Patients with Brain Tumors
Anesth. Analg., February 1, 2002; 94(2): 389 - 392.
[Abstract] [Full Text] [PDF]


Disclaimer: Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.