British Journal of Anaesthesia, 1995, Vol. 74, No. 5 509-511
© 1995 The Board of Management and Trustees of the British Journal of Anaesthesia
research-article |
Low-dose droperidol reduces postoperative vomiting in paediatric day surgery
Shackleton Department of Anaesthesia, Southampton General Hospital Tremona Road, Southampton SO9 4XY
Department of Medical Statistics and Computing Southampton General Hospital Tremona Road, Southampton SO9 4XY
*Address for correspondence: Department of Anaesthesia, Royal Naval Hospital, Stonehouse, Plymouth PL1 3JY
In a prospective, randomized, blind study, we assessed the effectiveness of droperidol 20 µg kg1 i.v., given at induction of anaesthesia, in preventing postoperative vomiting in paediatric day-case patients. We studied 270 children, aged 115 yr. undergoing body surface surgery. There was a significant reduction in the incidence of vomiting in the recovery room (1.4% vs 9.2%, P < 0.005) and in the day ward (9.4% vs 18.3%, P < 0.05) in patients receiving droperidol. There was no significant difference on the journey home (9.5% vs 17.83%, ns) or at home (16.7% vs 10.3%, ns). There was also a reduction in the severity of vomiting in the droperidol group. There were no adverse side effects. (Br. J. Anaesth. 1995; 74: 509511)