Skip Navigation

This Article
Right arrow Full Text (PDF)
Right arrow E-Letters: Submit a response to the article
Right arrow Alert me when this article is cited
Right arrow Alert me when E-letters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrow Search for citing articles in:
ISI Web of Science (2)
Right arrowRequest Permissions
Right arrow Disclaimer
Google Scholar
Right arrow Articles by LOAN, P. B.
Right arrow Articles by MCMURRAY, T. J.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by LOAN, P. B.
Right arrow Articles by MCMURRAY, T. J.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

British Journal of Anaesthesia, 1995, Vol. 74, No. 3 330-332
© 1995 The Board of Management and Trustees of the British Journal of Anaesthesia

other

Comparison of the haemodynamic effects of mivacurium and atracurium during fentanyl anaesthesia

P. B. LOAN, MRCP, FRCA, P. ELLIOTT, MD, FRCA, R. K. MIRAKHUR, MD, PHD, FRCA, H. F. BUNTING, FEARCSI, S. BHANUMURTHY, MD, FFARCSI and T. J. MCMURRAY, MD, FRCA

Department of Anaesthetics, Queen's University of Belfast, Whitla Medical Building 97 Lisburn Road, Belfast BT9 7BL
Department of Anaesthetics, Royal Hospitals Trust Belfast

Correspondence to R.K.M.

We have measured the haemodynamic effects of mivacurium 0.15 and 0.2 mg kg–1, and atracurium 0.5 mg kg–1 administered over 10–15 s in patients undergoing coronary artery bypass surgery under fentanyl anaesthesia. There were no significant haemodynamic changes in the atracurium group, other than a transient decrease in pulmonary arterial wedge pressure. Changes in heart rate were small in all three groups. Mivacurium 0.15 mg kg–1 produced changes of only small magnitude (12% decrease in mean arterial pressure and 16% decrease in systemic vascular resistance index) however, mivacurium 0.2 mg kg–1 produced a 25% reduction in mean arterial pressure, a 14% increase in cardiac index and a 35% decrease in systemic vascular resistance index. Erythema developed in two, three and seven patients after atracurium, mivacurium 0.15mgkg–1 and mivacurium 0.2 mg kg–1, respectively. One patient exhibited a 54% decrease in mean arterial pressure, generalized erythema and bronchospasm after mivacurium 0.2mg kg–1. The haemodynamic changes with mivacurium suggested histamine release. (Br. J. Anaesth. 1995; 74: 330–332)


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?




Disclaimer: Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.