British Journal of Anaesthesia, 1994, Vol. 73, No. 3 342-344
© 1994 The Board of Management and Trustees of the British Journal of Anaesthesia
research-article |
Influence of serum concentrations of catecholamines and i.v. or volatile anaesthesia on evoked electromyography in the hand
Department of Anaesthesia Western Infirmary, Glasgow G11 6NT
Address for correspondence: Shackleton Department of Anaesthesia, Southampton General Hospital, Tremona Road, Southampton SO9 4XY
We have examined the correlation between serum concentrations of catecholamines and the evoked electromyographic (EEMG) response from the first dorsal interosseous muscle of the hand in 20 patients during minor surgery under propofol or enflurane anaesthesia without neuromuscular blocking drugs. The supinated forearm, with the wrist fully extended, was strapped firmly to an armboard and immobilized with adhesive tape. In the propofol group, the mean EEMG response to the first stimulus in the train-of-four (T1) decreased to 83.0% (95% confidence intervals (Cl) 78.787.3%) of baseline, while in the enflurane group the mean EEMG Ti response decreased to 84.0% (95% Cl 81.686.4%) of baseline. The decrease in the EEMG response occurred over 20 min and did not correlate with plasma concentrations of adrenaline or noradrenaline (correlation coefficients all <0.26). We conclude that the decrease in EEMG response during the first 30 min of anaesthesia occurred during both i.v. and inhalation anaesthesia, and that changes in plasma concentrations of catecholamines did not cause the decrease in the EEMG response.