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British Journal of Anaesthesia, 1993, Vol. 70, No. 3 365-367
© 1993 The Board of Management and Trustees of the British Journal of Anaesthesia

letter

TEST-TUBE EQUILIBRATION OF VOLATILE ANAESTHETIC CONCENTRATIONS

D. C. MARTIN, M.D., J. K. PRUETT, PH.D and R. S. ARONSTAM, PH.D

Departments of Anesthesiology and Pharmacology and Toxicology, Medical College of Georgia Augusta, GA 30912-2227, U.S.A

Correspondence to D.C.M.

We have measured concentrations of volatile anaesthetics after injection into test-tube assay solutions. In non-agitated tubes, aqueous anaesthetic concentrations decreased significantly throughout 40 min of incubation. Agitation (20-s vortex) of the tubes decreased the aqueous anaesthetic concentration by approximately 80% from concentrations in non-agitated tubes and resulted in more stable liquid anaesthetic concentrations over time. A decrease of less than 15% occurred between 10 and 50 min of incubation. (Br. J. Anaesth. 1993; 70: 365–367)


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