Skip Navigation

This Article
Right arrow Full Text (PDF)
Right arrow E-Letters: Submit a response to the article
Right arrow Alert me when this article is cited
Right arrow Alert me when E-letters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrowRequest Permissions
Right arrow Disclaimer
Google Scholar
Right arrow Articles by MASON, D. G.
Right arrow Articles by LLOYD-THOMAS, A. R.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by MASON, D. G.
Right arrow Articles by LLOYD-THOMAS, A. R.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

British Journal of Anaesthesia, 1992, Vol. 69, No. 6 567-569
© 1992 The Board of Management and Trustees of the British Journal of Anaesthesia

research-article

SEQUENTIAL MEASUREMENT OF THE MEDIAN NERVE SOMATOSENSORY EVOKED POTENTIAL DURING ISOFLURANE ANAESTHESIA IN CHILDREN{dagger}

D. G. MASON, M.B., B.S., F.R.C.ANAES.1,*, D. HIGGINS, M.B., B.S., F.R.C.ANAES.1,§, S. G. BOYD, M.D.2 and A. R. LLOYD-THOMAS, M.B., B.S., F.R.C.ANAES.1

1Department of Anaesthetics, Hospitals for Sick Children Great Ormond Street, London WC1N 3JR
2Department of Clinical Neurophysiology, Hospitals for Sick Children Great Ormond Street, London WC1N 3JR

We have used sequential measurements of median nerve somatosensory evoked potentials (mnSSEP) in 10 children to estimate the equilibration time of an inhalation anaesthetic agent between alveolar gas, arterial blood and brain. MnSSEP were obtained sequentially every 90–180 s. After control measurements in the absence of isoflurane, the end-tidal concentration was increased stepwise (0.25, 0.5 and 0.75 MAC). Each isoflurane concentration was maintained for 15 min. The point at which the N20 latency reached stability was determined; the mean time between reaching a stable end-tidal isoflurane concentration and this point varied between 5 min 16 s and 7 min 37 s. This technique may be useful in circumstances in which a "steady state" of anaesthesia is important, such as in the determination of MAC or during intraoperative monitoring of evoked potentials.

*Nuffield Department of Anaesthetics, The John Radcliffe Hospital, Headington, Oxford, OX3 9DU.

§Department of Anaesthetics, University College Hospital, London, WC1E 6AU.

{dagger}Presented in part at the Anaesthetic Research Society, November 1990 (British Journal of Anaesthesia 1991; 66: 399P)


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?




Disclaimer: Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.