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British Journal of Anaesthesia, 1992, Vol. 69, No. 5 522-525
© 1992 The Board of Management and Trustees of the British Journal of Anaesthesia

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BACTERIAL RETENTION PROPERTIES OF HEAT AND MOISTURE EXCHANGE FILTERS

M. G. LEE, B.PHARM, PH.D., M.R.PHARM.S., M.R.S.C, C.CHEM.1,*, J. L. FORD, B.SC., PH.D., M.R.PHARM.S.2, P. B. HUNT, B.SC., C.BIOL., M.I.BIOL.3, D. S. IRELAND, B.SC., PH.D.4 and P. W. SWANSON, B.SC, C.HNG., M.R.A.E.S., P.G.C.E.4

1Mersey Regional Health Authority Hamilton House, 24 Pall Mall, Liverpool L3 6AL
2School of Pharmacy, The Liverpool John Moores University Byrom Street, Liverpool L3 3AF
3Pharmaceutical Microbiology Laboratory, Whiston Hospital Prescot, Merscyside L35 5DR
4QC Laboratory, Countess of Chester Hospital Liverpool Road, Chester CHI 2BA

*Correspondence to M.G.L.

We have examined the properties of six heat and moisture exchange filters (HMEF) to ascertain their resistance to liquid flow and their ability to retain a challenge bacterium, Pseudomonas diminuta, from aqueous and nebulized suspensions. Only one HMEF, the Pall Ultipor was able to withstand a significantly greater pressure of liquid than that found in clinical practice. However, when breached, the HMEF were unable to prevent transmission of micro-organisms from aqueous suspension. Only the Darex Hydrobac filter failed to meet the manufacturer's claim for filter efficiency for nebulized bacteria, mainly because the filter housing failed under test. When the reduction in bacterial cells after passage of the nebulized Pseudomonas diminuta through the HMEFs was analysed statistically, the data showed that the HMEF produced by Pall (Ultipor) and Intersurgical (Filter therm) were superior to those produced by DAP, Mediplan (Hygrobac), Intertech (HME 225–2835–800) and Gibeck (Humid-vent). (Br. J. Anaesth. 1992;69:522–525)


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