Skip Navigation

This Article
Right arrow Full Text (PDF)
Right arrow E-Letters: Submit a response to the article
Right arrow Alert me when this article is cited
Right arrow Alert me when E-letters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrowRequest Permissions
Right arrow Disclaimer
Google Scholar
Right arrow Articles by PLATT, M.
Right arrow Articles by HIRSCH, N.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by PLATT, M.
Right arrow Articles by HIRSCH, N.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

British Journal of Anaesthesia, 1991, Vol. 66, No. 1 45-47
© 1991 The Board of Management and Trustees of the British Journal of Anaesthesia

research-article

EFFECT OF ARTERIAL CARBON DIOXIDE TENSION ON THE DURATION OF ACTION OF ATRACURIUM

M. PLATT, F.C.ANAES.*, A. HAYWARD, F.C.ANAES., A. COOPER, P.C.ANAES. and N. HIRSCH, F.C.ANAES.

The National Hospital for Nervous Diseases Queen Square, London WC1N 3BG

*Present address, for correspondence: Department of Anaesthesia, St Mary's Hospital, Praed Street, London W2 1NY.

The duration of action of atracurium was studied in two groups of patients. In group l (n = 15), patients' lungs were hyperventilated to a mean PaCo2 of 3.3 kPa and in group II (n = 15) lungs were ventilated to maintain a mean PaCo2 of 5.3 kPa. Anaesthesia was maintained using an infusion of propofol. The time taken to return to a T1 twitch height of 10% of control was measured following each incremental dose of atracurium 0.15 mg kg–1. It was found that the duration of action of atracurium was significantly (P < 0.0005) shorter in the hypocapnic group.


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?




Disclaimer: Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.