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British Journal of Anaesthesia, 1988, Vol. 61, No. 5 611-616
© 1988 The Board of Management and Trustees of the British Journal of Anaesthesia

research-article

BENZODIAZEPINE PREMEDICATION IN MINOR DAY-CASE SURGERY: COMPARISON OF ORAL MIDAZOLAM AND TEMAZEPAM WITH PLACEBO

J. HARGREAVES, M.B., CH.B., F.F.A.R.C.S

Department of Anaesthesia, University Hospital of South Manchester Manchester M20 8LR

Ninety day-case or short stay patients were allocated to three groups in a double-blind study. The groups received oral midazolam 15 mg, oral temazepam 20 mg or placebo approximately 1 h before surgery. Midazolam was superior to temazepam regarding anxiolysis, sedation and amnesia, but temazepam was superior to placebo. However, delay in immediate and late recovery occurred significantly more often in the patients receiving midazolam than in those receiving temazepam or placebo.


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