Skip Navigation

This Article
Right arrow Full Text (PDF)
Right arrow E-Letters: Submit a response to the article
Right arrow Alert me when this article is cited
Right arrow Alert me when E-letters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrowRequest Permissions
Right arrow Disclaimer
Google Scholar
Right arrow Articles by RIDLEY, S. A.
Right arrow Articles by BRAUDE, N.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by RIDLEY, S. A.
Right arrow Articles by BRAUDE, N.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

British Journal of Anaesthesia, 1988, Vol. 61, No. 5 551-556
© 1988 The Board of Management and Trustees of the British Journal of Anaesthesia

research-article

POST-TETANIC COUNT AND INTENSE NEUROMUSCULAR BLOCKADE WITH VECURONIUM IN CHILDREN

S. A. RIDLEY, M.B., B.S., F.F.A.R.C.S.* and N. BRAUDE, M.B., CH.B., M.R.C.P., F.F.A.R.C.S.

The Hospitals For Sick Children Great Ormond Street, London WCIN 3JH

Sixty children undergoing surgery were allocated, according to weight, to three equal groups. Each child received a loading dose of vecuronium 80 µg kg–1 followed immediately by an infusion set initially at 1.4 µg kg–1 min–1. The subsequent intense neuromuscular blockade was assessed using the post-tetanic count (PTC). Maintaining the PTC between 5 and 15 ensured adequate paralysis which was antagonized easily 6–18 min after stopping the infusion. However, the duration of the initial intense block was unpredictable and the use of a peripheral nerve stimulator is advisable, particularly in smaller infants (<5 kg). The results suggest that vecuronium accumulated after 3 h infusion and that has less presynaptic effect than atracurium.

*Present address for correspondence: Clinical Shock Study Team, Western Infirmary, Glasgow G11 6NT.


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 Anesth. Analg.Home page
W. M. Splinter and L. A. Isaac
The Pharmacoeconomics of Neuromuscular Blocking Drugs: A Perioperative Cost-Minimization Strategy in Children
Anesth. Analg., August 1, 2001; 93(2): 339 - 344.
[Abstract] [Full Text] [PDF]


Disclaimer: Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.