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British Journal of Anaesthesia, 1988, Vol. 61, No. 3 292-296
© 1988 The Board of Management and Trustees of the British Journal of Anaesthesia

research-article

EFFECT OF SUXAMETHONIUM GIVEN DURING RECOVERY FROM ATRACURIUM

R. P. F. SCOTT, B.SC., M.B., CH.B., F.F.A.R.C.S. and J. NORMAN, M.B., CH.B., PH.D., F.F.A.R.C.S., F.F.A.R.A.C.S.

Shackleton Department of Anaesthetics, The University and the General Hospital Southampton SO9 4XY

Correspondence to R.S.

Suxamethonium was given in varying doses when twitch response had returned to 50% of control following the administration of atracurium in anaesthetized patients. Small doses of suxamethonium produced antagonism, enhancement of the block, or a combination showing a biphasic response. A dose of 3 mg kg–1 was needed to produce consistently 100% block of the twitch. The subsequent recovery rate for T1 was as fast as that seen normally after suxamethonium and was not enhanced by neostigmine.


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