British Journal of Anaesthesia, 1988, Vol. 61, No. 3 250-254
© 1988 The Board of Management and Trustees of the British Journal of Anaesthesia
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MATERNAL INSPIRED OXYGEN CONCENTRATION AND NEONATAL STATUS FOR CAESAREAN SECTION UNDER GENERAL ANAESTHESIA
Comparison of Effects of 33% or 50% Oxygen in Nitrous Oxide
Sir Humphry Davy, Department of Anaesthetics Bristol Royal Infirmary Bristol
*Present address, for correspondence: Shackleton Department of Anaesthetics, Southampton General Hospital, Southampton SO9 4XY.
The relationship between maternal F1O2 and umbilical venous PO2, PCO2, pH and neonatal Apgar and TSR (time to sustained respiration) scores was studied in 35 patients undergoing Caesarean section under general anaesthesia. Patients were allocated randomly to breathe an FlO2 of either 0.5 or 0.33. Umbilical venous blood was collected at the time of delivery, and TSR and 1- and 5-min Apgar scores recorded. Mean values for umbilical venous blood were: PO2 3.9 kPa and 3.7 kPa; PC02 6.2 kPa and 6.2 kPa; pH 7.30 and 7.31 (50% and 33% groups, respectively (P > 0.05)). No differences were found between groups for 1- or 5-min Apgar scores or TSR values. It is concluded that no difference in fetal outcome or acid-base status can be detected when maternal FIO2 is decreased from 0.5 to 0.33, and that the use of 33% oxygen in 66% nitrous oxide appears to be safe for neonates who have not suffered fetal distress before delivery.
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