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British Journal of Anaesthesia, 1988, Vol. 60, No. 5 592-594
© 1988 The Board of Management and Trustees of the British Journal of Anaesthesia

case-report

APNOEA ASSOCIATED WITH THE INTRATHECAL ADMINISTRATION OF MORPHINE IN OBSTETRICS

E. ABOULEISH, M.B., CH.B., M.D.

The University of Texas Health Science Center at Houston, Medical School Department of Anesthesiology 6431 Fannin, MSMB 5.020, Houston, TX 77030, U.S.A.

The intrathecal administration of hyperbaric morphine 1 mg for pain relief during labour was followed, 7 h after injection, and 1 h after delivery, by respiratory depression. Pulseoximetry was helpful in alerting the medical personnel. After an initial 1 mg of naloxone i.v. in increments of 0.1–0.2 mg, a continuous infusion of naloxone 0.4 mg h–1 i. v. was used to prevent a recurrence of the respiratory depression. The total dose of naloxone over an 8-h period was 3.6 mg.


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