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British Journal of Anaesthesia, 1988, Vol. 60, No. 5 520-524
© 1988 The Board of Management and Trustees of the British Journal of Anaesthesia

research-article

COMPARISON OF THE RECOVERY CHARACTERISTICS OF DIAZEPAM AND MIDAZOLAM

D. GALLETLY, F.F.A.R.A.C.S., F.F.A.R.C.S., P. FORREST, M.B., CH.B. and G. PURDIE, B.SC.

Department of Anaesthesia, Wellington Clinical School of Medicine Wellington, New Zealand

Correspondence to D.C.G.

A double-blind crossover comparison of efficacy and recovery from midazolam 5 mg and diazepam (in propylene glycol) 10 mg was undertaken in eight volunteer subjects. It was found that midazolam was significantly more potent in this dose ratio than diazepam. helping to explain the finding of previous studies that the recovery from midazolam and diazepam in a 1:2 dose ratio is comparable.


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