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British Journal of Anaesthesia, 1988, Vol. 60, No. 2 157-160
© 1988 The Board of Management and Trustees of the British Journal of Anaesthesia

research-article

EFFECT OF SUXAMETHONIUM ON THE ICP OF CATS WITH AND WITHOUT THIOPENTONE PRETREATMENT

S. THIAGARAJAH, M.D., F.F.A.R.C.S., S. SOPHIE, M.D., E. LEAR, M.D., I. AZAR, M.D. and E. A. M. FROST, M.B., CH.B.

Department of Anesthesiology, Beth Israel Medical Center First Avenue at 16th Street, New York, N.Y. 10003. Albert Einstein College of Medicine 1300 Morris Park Avenue, Bronx, N.Y. 10461, U.S.A.

Correspondene to S.T., Beth Isreal Medical Center

Twelve cats were assigned equally to two groups, one with normal, and the other with artificially-increased intracranial pressure. When suxamethonium was administered to these animals, the intracranial pressure increased in both groups, irrespective of their baseline intracranial pressure. When the same dose of suxamethonium was administered after pretreatment with thiopentone in both groups of animals, the intracranial pressure again increased from the control values.


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