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British Journal of Anaesthesia, 1988, Vol. 60, No. 1 43-47
© 1988 The Board of Management and Trustees of the British Journal of Anaesthesia

research-article

OUTCOME AFTER GENRAL ANAESTHESIA FOR REPAIR OF FRACTURED NECK OF FEMUR

A Randomized Trial of Spontaneous V. Controlled Ventilation

S. A COLEMAN, M.B., CH.B., F.F.A.R.C.S.*, W. J. BOYCE, M.A., M.Sc., M.R.C.P., M.F.C.M.{dagger}, P. H. COSH, M.N., B.CH., F.F.A.R.C.S. and P. J. MCKENZIE, M.D., F.F.A.R.C.S.

Nuffield Department of Anaesthetics, John Radcliffe Hospital Headington, Oxford OX3 9DU.

Correspondence to P.J. McK.

One hundred and fifty-two patients undergoing surgery for fractured neck of femur were randomly allocated to receive either general anaesthesia with spontanoeous ventilation with nitrous oxide and halothane in oxygen or general anaesthesia with controlled ventilation with fentanyl, nitrous oxide and halothane in oxygen. Atracurium was used to provide muscle paralysis in 65% of the latter group, the remained receiving no neuromuscular blocking agent other than suxamethonium for intubation. Patients were followed up for 6 months. Mortality and outcome were not significantly different between the groups. Overall mortality at 4 weeks was 5.2% and at 6 months was 15.1%—figures which are considerably lower than in some other comparable studies. This study does not support the suggestion that general anaesthesia with controlled ventilation is associated with increased postoperative mortality.

*Department of Anaesthetics, Royal Devon & Exeter (Wonford), Exeter.

{dagger}Acting District Medical Officer, Northampton Health Authority.


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