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British Journal of Anaesthesia, 1988, Vol. 60, No. 1 109-111
© 1988 The Board of Management and Trustees of the British Journal of Anaesthesia

case-report

SAFE USE OF PROPOFOL IN A PATIENT WITH ACUTE INTERMITTENT PORPHYRIA

G. MITTERSCHIFFTHALER, M.D., A. THEINER, M.D., H. HETZEL, M.D. and L. C. FUITH, M.D.

Department of Anaesthesia, University Hospital Anichstrasse 35, A-6020 Innsbruck, Austria.
Department of Obstetrics and Gynaecology, University Hospital Anichstrasse 35, A-6020 Innsbruck, Austria.

On two occasions a patient suffering from acute intermittent porphyria (AIP) was anaesthetized with propofol as the sole agent. The concentrations of urinary porphobilinogen. porphyrins and porphyrin precursors did not exceed preoperative values, and no exacerbation of the disease was noted.


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