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British Journal of Anaesthesia, 1987, Vol. 59, No. 6 678-682
© 1987 The Board of Management and Trustees of the British Journal of Anaesthesia

other

EFFECTS OF FASTING AND ORAL PREMEDICATION ON THE pH AND VOLUME OF GASTRIC ASPIRATE IN CHILDREN

G. MEAKIN, M.B., CH.B., D.A. F.F.A.R.C.S, A. E. DINGWALL, M.B., CH.B., F.F.A.R.C.S* and G. M. ADDISON, M.A., M.B., B.CHIR., PH.D.

Department of Anaesthesia, Royal Manchester Children's Hospital Pendlebury, Manchester M27 1HA.

*Present address: Stepping Hill Hospital, Stockport, Cheshire SK2 7JE.

The pH and volume of gastric aspirate were measured immediately after the induction of anaesthesia in 224 healthy children to determine the effects of decreasing the period of fasting and of giving oral premedicants before anaesthesia. Fasting for less than 4 h was found to increase the volume of gastric aspirate and the risk of developing pulmonary aspiration syndrome. Trimeprazine syrup was found to increase the pH of the gastric contents, and decrease the likelihood of the pulmonary aspiration syndrome. There was a significant increase in gastric volume in patients premedicated with temazepam elixir which did not occur in patients given temazepam capsules. These results support the custom of fasting patients for at least 4 h before anaesthesia and indicate that oral premedicants and their vehicles can have significant effects on the stomach.


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 Anesth. Analg.Home page
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