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British Journal of Anaesthesia, 1986, Vol. 58, No. suppl_1 91S-95S
© 1986 The Board of Management and Trustees of the British Journal of Anaesthesia

other

Pseudocholinesterase Activity and Atracurium V. Suxamethonium Block

A. Baraka, M.B., B.C., D.A., D.M., M.D., N. Wakid, PH.D., R. Noueihed, M.D., H. Karam, M.D. and N. Bolotova, M.D.

Departments of Anesthesiology and Clinical Chemistry, American University Medical Center Beirut, Lebanon

Abstract

Serum pseudocholinesterase activity in pregnant women was assayed spectrophotometrically using either propionylthiocholine or suxamethonium as substrate. All patients had a normal phenotype as indicated by normal dibucaine and fluoride numbers. However, the mean cholinesterase activity was lower than in the general population. There was a negative correlation between cholinesterase activity and the duration of neuromuscular blockade following suxamethonium, but no correlation was observed between the cholinesterase activity and the duration of block following atracurium.


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