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British Journal of Anaesthesia, 1986, Vol. 58, No. 4 437-440
© 1986 The Board of Management and Trustees of the British Journal of Anaesthesia

other

EFFECTS OF VECURONIUM BROMIDE ON INTRACRANIAL PRESSURE AND CEREBRAL PERFUSION PRESSURE

A Preliminary Report

G. ROSA, M.D., M. SANFILIPPO, M.D., V. VILARDI, M.D., P. ORFEI, M.D. and A. GASPARETTO, M.D.

Department of Anaesthesiology and Intensive Care 2nd State University of Rome "Tor Vergata", Roma, Italy
Istitutodi Anestesiologiae Rianimazione, Università di Roma "La Sapienza" v.le del Policlinico, 00161 Roma, Italia

The effects of vecuronium 0.1 mg kg–1 on intracranial pressure, heart rate and arterial pressure were evaluated in 20 anaesthetized patients with intracranial tumours undergoing neurosurgery. Apart from a slight decrease in intracranial pressure (–4.9%; ns) which was most probably the result of a concomitant decrease (–14.9%) in central venous pressure, vecuronium 0.1mg kg–1 was without effect on either cerebral or systemic haemodynamics.


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