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British Journal of Anaesthesia, 1985, Vol. 57, No. 8 725-731
© 1985 The Board of Management and Trustees of the British Journal of Anaesthesia

research-article

COMPARISION OF THE NEW EMULSION FORMULATION OF PROPOFOL WITH METHOHEXITONE AND THIOPENTONE FOR INDUCTION OF ANAESTHESIA IN DAY CASES

N. MACKENZIE, M.B., CH.B., F.F.A.R.C.S and I. S. GRANT, M.B., CH.B., M.R.C.P., F.F.A.R.C.S

Department of Anaesthetics, Ninewells Teaching Hospital Dundee

The new emulsion formulation of di-isopropyl phenol (propofol) was compared with metho-hexitone and thiopentone for induction of anaesthesia in day cases. Propofol produced significantly smoresearch-article induction of anaesthesia, but caused more cardiovascular and respiratory depression. Pain on injection was significantly less than with methohexitone. Post-anaesthetic recovery was superior with propofol, with virtual absence of side effects, and rapid recovery with little impairment of psychomotor function 30 min after anaesthesia.


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