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British Journal of Anaesthesia, 1985, Vol. 57, No. 6 569-572
© 1985 The Board of Management and Trustees of the British Journal of Anaesthesia

research-article

CHANGES IN VENTILATORY PATTERNS DURING HALOTHANE ANAESTHESIA IN CHILDREN

I. MURAT, M.D., M. M. DELLEUR, M.D., K. MACGEE, M.D. and C. SAINT-MAURICE, M.D.

Département d'Anesthésie-Réanimation Chirurgicale Hôpital Saint-Vincent-de-Paul, 74, avenue, Denfert-Rochereau, 75674 Paris Cédex 14, France

Changes in ventialtory variables (VE, VE, f, T1/Ttot. VT/T1. PE'co2) were studied in 12 unpremeicated children, weighing between 10 and 20 kg, during halothane anaesthesia. at an inspired concentration of 0.5% halothane, respiratory rate increased, VT decreased, and VE did not change markedly. When the inspired.; halothane concentration increased further, there was a significant decrease in VE, mainly as a result of a marked decrease inVT. PE'CO2 increased significantly and inspiratory duty cycle decreased at high inspired halothane concentrations. On return to baseline (0.5% halothane), there was a significant decrease in inspiratory timing and a significant increase in PE'CO2- The relations between these changes and the effect of halothane on inspiratory muscles are discussed.


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