Skip Navigation

This Article
Right arrow Full Text (PDF)
Right arrow E-Letters: Submit a response to the article
Right arrow Alert me when this article is cited
Right arrow Alert me when E-letters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrow Search for citing articles in:
ISI Web of Science (12)
Right arrowRequest Permissions
Right arrow Disclaimer
Google Scholar
Right arrow Articles by SIVALINGAM, T.
Right arrow Articles by PLEUVRY, B. J.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by SIVALINGAM, T.
Right arrow Articles by PLEUVRY, B. J.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

British Journal of Anaesthesia, 1985, Vol. 57, No. 4 430-433
© 1985 The Board of Management and Trustees of the British Journal of Anaesthesia

research-article

ACTIONS OF MORPHINE, PETHIDINE AND PENTAZOCINE ON THE OESTRUS AND PREGNANT RAT UTERUS IN VITRO

T. SIVALINGAM, M.D., F.F.A.R.C.S. and B. J. PLEUVRY, B.PHARM., M.SC., PH.D.

Department of Anaesthesia and Pharmacology, University of Manchester Stopford Building, Manchester MB 9PT

The effects of morphine, pethidine and pentazocine have been studied on the rat uterus in vitro. Morphine caused a concentration-dependent decrease in the frequency of contraction of the oestrus uterus. In contrast, both pethidine and pentazocine enhanced the contraction rate. The pregnant uterus showed little response to morphine in the concentrations studied, whereas there was an augmented response to the stimulant actions of pethidine and pentazocine. Naloxone 1–100 ng ml–1 was unable to antagonize the uterine responses to the opioids, but higher concentrations of naloxone, when administered alone, slowed the frequency of the myogenic activity.


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 NEJMHome page
C. A. Wong, B. M. Scavone, A. M. Peaceman, R. J. McCarthy, J. T. Sullivan, N. T. Diaz, E. Yaghmour, R-J. L. Marcus, S. S. Sherwani, M. T. Sproviero, et al.
The Risk of Cesarean Delivery with Neuraxial Analgesia Given Early versus Late in Labor
N. Engl. J. Med., February 17, 2005; 352(7): 655 - 665.
[Abstract] [Full Text] [PDF]

Home page
 Anesth. Analg.Home page
K. Y. Yoo, J. Lee, H. S. Kim, and S. W. Jeong
The Effects of Opioids on Isolated Human Pregnant Uterine Muscles
Anesth. Analg., April 1, 2001; 92(4): 1006 - 1009.
[Abstract] [Full Text] [PDF]


Disclaimer: Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.