Skip Navigation

This Article
Right arrow Full Text (PDF)
Right arrow E-Letters: Submit a response to the article
Right arrow Alert me when this article is cited
Right arrow Alert me when E-letters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrowRequest Permissions
Right arrow Disclaimer
Google Scholar
Right arrow Articles by McQUAY, H. J.
Right arrow Articles by LLOYD, J. W.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by McQUAY, H. J.
Right arrow Articles by LLOYD, J. W.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

British Journal of Anaesthesia, 1985, Vol. 57, No. 4 412-419
© 1985 The Board of Management and Trustees of the British Journal of Anaesthesia

research-article

ZOMEPIRAC, DIHYDROCODEINE AND PLACEBO COMPARED IN POSTOPERATIVE PAIN AFTER DAY-CASE SURGERY

The relationship between the effects of single and multiple doses

H. J. McQUAY, F.F.A.R.C.S., R. E. S. BULLINGHAM, F.F.A.R.C.S., R. A. MOORE, D. PHIL., DAWN CARROLL, S.R.N., P. J. D. EVANS, F.F.A.R.C.S., GERALDINE O'SULLIVAN, F.F.A.R.C.S., J. COLLIN, M.D. and J. W. LLOYD, F.F.A.R.C.S.

Pain Relief Research Unit, Oxford Regional Pain Relief Unit, Abingdon Hospital Abingdon, Oxford OX14 1AG
Nuffield Department of Surgery, John Radcliffe Hospital Oxford

Correspondence to H. J. McQ.

Zomepirac 100 mg and dihydrocodeine 30 mg were compared with placebo in a controlled randomized, double-blind, single-dose postoperative study. Patients continued to receive either zomepirac or dihydrocodeine for pain relief for 5 days at home in a double-blind study, being allowed to titrate the consumption of tablets to their degree of pain. The efficacy and side effects of the medication were evaluated. In the singledose phase, both active treatments were significantly better than placebo. In the multiple dosing phase, zomepirac was statistically better than dihydrocodeine. Non-parametric statistical tests indicated highly significant correlations between single- and multiple-dose analgesic measurements for both zomepirac and dihydrocodeine.

Present address Charing Cross Hospital, London.


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?




Disclaimer: Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.