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British Journal of Anaesthesia, 1985, Vol. 57, No. 3 271-274
© 1985 The Board of Management and Trustees of the British Journal of Anaesthesia

research-article

BUPRENORPHINE-SUPPLEMENTED ANAESTHESIA

Influence of Dose on Duration of Analgesia after Cholecystectom

DORIT OBEL, M.D., L. K. HANSEN, M.D., M. S. HÜTTEL, M.D. and P. K. ANDERSEN, M.D.

Department of Anaesthetics, Odense University Hospital Dk-5000 Odense C, Denmark

Fifty-one patients undergoing cholecystectomy received a single dose of buprenorphine 4.5-12 µg kg–1 at induction. Median duration of analgesia after surgery was 6 h. Multiple regression analysis showed the duration of analgesia to be slightly dependent on the age of the patient. No relationship was found between the duration of analgesia and the weight-related dose of buprenorphine, the age, sex or body weight of the patient, the duration of anaesthesia, or the dose of droperidol or thiopentone administered.


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