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British Journal of Anaesthesia, 1985, Vol. 57, No. 3 259-263
© 1985 The Board of Management and Trustees of the British Journal of Anaesthesia


research-article

COMPARISON OF INFUSIONS OF MORPHINE AND LYSINE ACETYL SALICYLATE FOR THE RELIEF OF PAIN FOLLOWING THORACIC SURGERY

R. M. JONES, F.F.A.R.C.S., J. N. CASHMAN, B.SC., F.F.A.R.C.S., M. G. FOSTER, F.F.A.R.C.S., J. R. WEDLEY, F.F.A.R.C.S. and A. P. ADAMS, PH.D., F.F.A.R.C.S.

Department of Anaesthetics, Guy's Hospital Medical School, (The United Medical and Dental Schools, University of London) London Bridge, London SE 1

Correspondence to R. M. J.

A double-blind study comparing the effectiveness of a continuous infusion i.v. of lysine acetyl salicylate (LAS) with an infusion of morphine for the treatment of pain following pulmonary surgery is described. Mean pain scores in the two groups were not significantly different at any stage during the 24-h period of study. LAS was not associated with any significantly greater blood loss in the period after operation. The incidence of drowsiness, nausea and vomiting, and the need for antiemetic medication were similar in both groups.


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