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British Journal of Anaesthesia, 1985, Vol. 57, No. 3 255-258
© 1985 The Board of Management and Trustees of the British Journal of Anaesthesia

research-article

COMPARISON OF INFUSIONS OF MORPHINE AND LYSINE ACETYL SALICYLATE FOR THE RELIEF OF PAIN AFTER SURGERY

J. N. CASHMAN, B.SC., F.F.A.R.C.S., R. M. JONES, F.F.A.R.C.S., M. G. FOSTER, F.F.A.R.C.S. and A. P. ADAMS, PH.D., F.F.A.R.C.S.

Department of Anaesthetics, Guy's Hospital Medical School, (United Medical and Dental Schools, University of London) London Bridge, London SE 1

Correspondence to J.N.C.

The effect of a constant i.v. infusion of lysine acetyl salicylate (LAS) on pain after operation was compared with that of a constant infusion of morphine in 30 patients undergoing unilateral inguinal herniorrhaphy. LAS provided analgesia equivalent to that provided by morphine and was associated with significantly less drowsiness, nausea and vomiting. No patient in either group was noted to suffer from respiratory depression. No untoward side effects were noted during or following the administration of LAS.


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