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British Journal of Anaesthesia, 1985, Vol. 57, No. 11 1104-1106
© 1985 The Board of Management and Trustees of the British Journal of Anaesthesia

research-article

ABSTAINING FROM CIGARETTE SMOKING HAS NO MAJOR EFFECT ON GASTRIC EMPTYING IN HABITUAL SMOKERS

O. U. PETRING, M.D*,, B. ADELHØJ, M.D, M. IBSEN, J. BRYNNUM and H. E. POULSEN, M.D

Department of Anaesthesiology, Kommunchospitalet DK-1399 Copenhagen K., Denmark
Medical Department A, Rigthospitalet (State University Hospital) DK-2100 Copenhagen Ø. , Denmark

*1Address for correspondence: Department of Anesthesia, Herlev Hospital, DK-2370 Herlev, Denmark.

The rate of liquid-phase gastric emptying was determined in seven smokers from the rate of paracetamol absorption after abstaining overnight from cigarettes, and again after smoking two cigarettes within 30 min. There were no significant differences between the maximum paracetamol concentration, the time to reach maximum paracetamol concentration, and the area under the plasma concentration-time curve from 0 to 120 min on the two occasions, indicating that abstaining from cigarette smoking had no major effect on gastric emptying in habitual smokers.


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