Skip Navigation

This Article
Right arrow Full Text (PDF)
Right arrow E-Letters: Submit a response to the article
Right arrow Alert me when this article is cited
Right arrow Alert me when E-letters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrow Search for citing articles in:
ISI Web of Science (47)
Right arrowRequest Permissions
Right arrow Disclaimer
Google Scholar
Right arrow Articles by FAHEY, M. R.
Right arrow Articles by HENNIS, P. J.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by FAHEY, M. R.
Right arrow Articles by HENNIS, P. J.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

British Journal of Anaesthesia, 1985, Vol. 57, No. 11 1049-1051
© 1985 The Board of Management and Trustees of the British Journal of Anaesthesia

research-article

EFFECT OF RENAL FAILURE ON LAUDANOSINE EXCRETION IN MAN

M. R. FAHEY, M.D.1, S. M. RUPP, M.D., C. CANFELL, M.S., D. M. FISHER, M.D., R. D. MILLER, M.D., M. SHARMA, M.D., K. CASTAGNOLI and P. J. HENNIS, M.D.

Departments of Anesthesia and Pharmacology, University of California San Francisco 94143.

1Address for correspondence: (M.R.F.), Department of Anesthesia, University of California, San Francisco, Ca 94143, U.S.A.

Patients with renal failure and undergoing a cadaver renal transplant were found to have plasma concentrations of laudanosine, following the administration of a single bolus dose of atracurium 0.5 mg kg-1, higher than those found in patients without renal failure. Since laudanosine is a known central nervous system stimulant in a variety of animal species, its actions should be investigated further in man, and particularly in patients with renal failure.


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 NEJMHome page
J. M. Hunter
New Neuromuscular Blocking Drugs
N. Engl. J. Med., June 22, 1995; 332(25): 1691 - 1699.
[Full Text] [PDF]


Disclaimer: Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.