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British Journal of Anaesthesia, 1982, Vol. 54, No. 5 539-546
© 1982 The Board of Management and Trustees of the British Journal of Anaesthesia

other

EFFECTS OF VARYING INSPIRATORY FLOW WAVEFORM AND TIME IN INTERMITTENT POSITIVE PRESSURE VENTILATION: PULMONARY OEDEMA

A B. BAKER, D PHIL (Oxon), F F A R.ACS, F F A R. C S*, J. B. THOMPSON, J TURNER and P. HASEN

Department of Anaesthesia, Otago University Dunedin, New Zealand
Nuffield Department of Anaesthetics, Oxford University Oxford (on Sabbatical Leave from Oxford University)
Department of Surgery, Queensland University Brisbane, Queensland, Australia
Department of Intensive Therapy, Repatriation General Hospital Greenslopes, Brisbane, Queensland, Australia

*Address for correspondence until September 1982: Nuffield Department of Anaesthetics, Oxford University, Oxford.

Greyhound dogs were given oleic acid 1. v to induce controlled pulmonary oedema. These animals were then studied using intermittent positive pressure ventilation (IPPV) with four different inspiratory flow waveforms, each at three different inspiratory times, in a fixed respiratory cycle of 4s at a constant tidal volume. Although there were statistically significant differences in airway and oesophageal pressures between the different waveforms and times, there was little variation in the other physiological parameters studied except for arterial carbon dioxide tension (PaCO2) which showed statistically significant improvement with reversed ramp and sine wave inputs and at the longer inspiratory time of 2.2s Venous admixture was also less with the longer inspiratory time of 2.2 s.


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