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British Journal of Anaesthesia, 1982, Vol. 54, No. 11 1175-1178
© 1982 The Board of Management and Trustees of the British Journal of Anaesthesia

research-article

URINARY RETENTION DURING I.M. AND EXTRADURAL MORPHINE ANALGESIA

T. K. PETERSEN, M D, S. E. HUSTED, M D, L. RYBRO, M D, B. A. SCHURIZEK, M D and M. WERNBERG, M D

Department of Anaesthesia and Internal Medicine, County Hospital of Aarhus DK-8000 Århus C, Denmark

Correspondence to S.E.H.

In the postoperative period fifty-six healthy patients undergoing cholecystectomy or operations for duodenal ulcer, received, in a randomized order, i.m , "high-level" or "low-level" extradural morphine Thirty-five per cent in the i m. group, 33% in the high-level group and 50% in the low-level group suffered urinary retention, in all cases within the first 24 h The mean cumulative dose of morphine necessary for pain relief was m the same range (13 4–16 5 mg) during the first 2 h of therapy for all groups, while the amounts after 24 and 48 h were twice to four times with the i m route compared with the extradural route. A peripheral effect of morphine on the urinary bladder is possible and the mechanism of action is discussed


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