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British Journal of Anaesthesia, 1980, Vol. 52, No. 2 197-198
© 1980 The Board of Management and Trustees of the British Journal of Anaesthesia

research-article

EFFECT OF ACUTE HYPOCAPNIA ON RENAL FUNCTION IN THE DOG ARTIFICIALLY VENTILATED WITH NITROUS OXIDE, OXYGEN AND HALOTHANE

J. M. HUNTER, M.B., CH.B., F.F.A.R.C.S., R. S. JONES, M.V.SC.M.R.C.V.S., D.V.A. and J. E. UTTING, M.A., M.B., F.F.A.R.C.

Department of Anaesthetics, Royal Liverpool Hospital P.O. Box 147, Liverpool, L69 3BX

Changes from normocapnia to hypocapnia (and vice versa) were induced in dogs lightly anaesthetized with nitrous oxide and halothane and subjected to passive pulmonary ventilation. During hypocapnia estimated renal plasma flow and urine production were greater than in normocapnia, and renal vascular resistance was decreased greatly compared with normocapnia. There was little change in glomerular filtration rate.


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